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If you’re craving something bold, creamy, and deeply comforting, this Cajun Chicken Pasta delivers every time. It combines tender seasoned chicken with a rich Cajun-spiced Alfredo sauce that clings to every strand of pasta.
This is the kind of dinner that feels like something you’d order at a restaurant — but it’s completely doable at home.
And if you already have our seasoned chicken recipe in your rotation, this is the perfect way to use it. The flavors layer beautifully, giving you heat, richness, and that unmistakable Cajun depth in every bite.
If you love bold pasta dishes, you’ll also want to try our garlic butter pasta or homemade Alfredo sauce next.
Why You’ll Love This Recipe
- Creamy, rich Alfredo-style sauce
- Bold Cajun flavor without overwhelming heat
- Perfect use for seasoned chicken
- Ready in about 30 minutes
- Family-friendly but easy to adjust spice level
Ingredients
- Fettuccine pasta
- Butter
- Heavy whipping cream
- Garlic
- Salt
- Black pepper
- Italian seasoning
- Cajun seasoning
- Freshly grated Parmesan cheese
- Optional diced tomatoes
- Cooked seasoned chicken
Equipment Needed
- Large pot — For cooking pasta in salted water.
- Large saucepan — Allows the cream sauce to simmer evenly.
- Balloon Whisk — Ensures the Parmesan melts smoothly.
- Microplane or fine grater — Freshly grated cheese creates the best texture.
- Colander — For draining pasta.
- Tongs — Helpful for tossing pasta directly in the sauce.
How to Make Cajun Chicken Pasta
The key to a smooth Cajun Alfredo sauce is gentle heat and proper layering.
Start by melting butter over medium-low heat. Adding the cream slowly and allowing it to gently simmer — not boil — keeps the sauce silky and prevents separation.
Once the cream is warmed and slightly thickened, stir in garlic and seasonings. Letting the Cajun seasoning bloom briefly in the warm cream intensifies its flavor and prevents a raw spice taste.
When adding Parmesan, reduce the heat and whisk gradually. This ensures the cheese melts evenly into the sauce rather than clumping.
Finally, toss the hot pasta directly into the skillet so it absorbs the sauce instead of simply being coated by it. If using diced tomatoes, add those in now too.
For the chicken, slice cooked seasoned chicken and stir it into the finished sauce just before serving. The warm sauce enhances the seasoning and ties everything together beautifully.
If you haven’t tried our seasoned chicken recipe yet, it’s an easy way to guarantee flavorful, juicy chicken every time.
This post may contain affiliate links. As an Amazon Associate, I earn from qualifying purchases.
PrintCajun Chicken Pasta (Creamy Cajun Alfredo)
This Creamy Cajun Alfredo Pasta blends rich, velvety Alfredo sauce with bold Cajun seasoning for the perfect balance of comfort and spice. Ready in about 25 minutes, it’s an easy weeknight dinner that feels restaurant-quality.
- Prep Time: 10 minutes
- Cook Time: 15 minutes
- Total Time: 25 minutes
- Yield: about 4 servings
- Category: Dinner, Pasta
- Cuisine: American
Ingredients
- 12 oz Homemade or store bought Fettuccine
- Prepared Garlic Herb Chicken Breast
- ½ cup butter
- 2 cups heavy whipping cream
- 3 cloves garlic, minced
- ½ tsp salt (adjust to taste)
- ½ tsp black pepper
- ½ tsp Italian seasoning
- 2 cups freshly grated Parmesan cheese
- 2 tsp cajun seasoning. (DIY tip – Make your own Cajun Seasoning!)
- Optional: shaved parmesan
- Optional: Diced tomatoes
Instructions
- Bring a large pot of salted water to a boil. Cook fettuccine according to instructions if using Homemade Pasta or to package directions if store bought until al dente. Reserve 1/2 cup pasta water before draining.
- In a large skillet or saucepan over medium-low heat, melt the butter.
- Add the heavy cream and bring to a gentle simmer. Cook for 3–4 minutes, stirring occasionally. Do not boil — gentle heat keeps the sauce smooth.
- Stir in the minced garlic, salt, black pepper, Italian seasoning, and Cajun seasoning. Cook about 1 minute, just until fragrant.
- Reduce heat to low and gradually whisk in the Parmesan cheese until fully melted and the sauce becomes velvety.
- If using, stir in the cream cheese until smooth.
- Simmer another 2–3 minutes until the sauce thickens enough to coat the back of a spoon.
- If the sauce becomes too thick, add a splash of reserved pasta water, additional cream, or milk to loosen.
- Toss immediately with hot pasta and diced tomatoes if using and serve. Can also be used as a base for chicken, shrimp, or vegetables.
- Top with cooked chicken breast and shaved parmesan if using.
Notes
Always use freshly grated Parmesan for the smoothest texture.
Keep the heat low to prevent separation.
Cajun blends vary in salt and spice — taste before adding more salt.
Pasta water is the best way to adjust thickness without thinning flavor.
Tips for Success
- Keep heat low when adding Parmesan to prevent graininess.
- Always use freshly grated cheese for smooth results.
- Taste before adding additional salt — Cajun seasoning varies in salt content.
- Add a splash of reserved pasta water if the sauce becomes too thick.
- Slice chicken thinly for the best texture in each bite.
Storage & Reheating
Store: Refrigerate in an airtight container for up to 3 days.
Reheat: Warm gently on the stovetop with a splash of cream or milk to restore smoothness.
Freeze: Not recommended — cream-based sauces can separate after freezing.
Frequently Asked Questions
Is Cajun Chicken Pasta very spicy?
It has a moderate kick balanced by the cream sauce. Adjust Cajun seasoning to suit your family’s preference.
Can I use store-bought rotisserie chicken?
Yes, though using our seasoned chicken recipe gives the best flavor.
Can I lighten the sauce?
You may substitute half-and-half, but the sauce will be thinner and slightly less rich.
What pasta works best?
Fettuccine is classic, but penne or linguine also hold the sauce well.
Variations & Serving Ideas
- Add sautéed shrimp for a Cajun surf-and-turf twist.
- Stir in fresh spinach at the end for color and balance.
- Top with freshly shaved Parmesan for a restaurant-style finish.
- Serve with warm bread with any of the recipes from our Bread Recipes
- Pair with a simple salad for an easy complete dinner.
Final Thoughts
Cajun Chicken Pasta is one of those meals that feels indulgent yet approachable. The creamy Alfredo base softens the spice while still delivering bold flavor — making it a reliable weeknight dinner that feels just a little elevated.
Once you make it, you’ll find yourself coming back to it anytime you want comfort food with personality.
Looking for a more basic Alfredo Sauce? Find it here!
If you make it please consider leaving a review. We love to see your posts! Tag us on Facebook, Instagram, or TikTok! @ourgratefulkitchen
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